Closed System Transfer Device


Closed System Drug Transfer Device

A Closed System Transfer Device is a device that is used for drug transfer, which automatically excludes the transfer of ecological contaminants into a system and the flight of vapor concentrations and harmful drug outside the system. 


A Closed System Drug-Transfer-Device‘s definition was initially published in NIOSH (National Institute for Occupational Safety and Health), an alert warning released by the US supervision.  The studies show that this alert warning was issued due to the association between working with hazardous drugs in a health-care environment and greater risk of increasing skin rashes, miscarriage, infant-birth defects and infertility, and also the possibility of getting leukemia and any other kind of cancer.  The alert warning issued by NIOSH recommends that a closed system transfer device be utilized when you are handling hazardous drugs. 

Although Powerful Chemotherapy drugs save people’s lives but exposure to residues, vapors, needle jabs etc may cause severe damage to the surroundings and effects severely to the people who work with these drugs every single day.  Also these toxic drugs cause increased risk of infertility and other health problems like cancer for all those medical professionals who work under these circumstances, who prepare, administer and dispense the toxic medicines. 

Closed System-Drug-Transfer-Device – CDC Suggestions:

Today, around 20% of U.S healthcare professionals are using Closed System Transfer Device on the suggestion of the CDC (Centers for Disease Control).  Now the technology has improved, and the chemotherapy market is presently the best in the pharmaceutical business. Euqashield an Israeli company marched into the filed in the year 2010 as it claims that the company has premeditated a unique, affordable safe and regulation-complaint solution. The products are CE and FDA approved for the Europe and United States, are presently used in various clinics and hospitals.

User-friendly and foolproof Device:

According to experts the Closed System transfer device is usually depends on a balloon or filter mechanism to balance the pressure in the container or Vial.  On the other hand, they are difficult to use and not completely protective for patients or workers, because they cannot prevent all drug vapors from evading or because they cannot keep infectivity from surrounding and getting into the vial. 

According to experts advice every member in the medical profession must attend a chemotherapy session, which helps them understand how to transfer hazardous medicine from vial-to-syringe, and then from syringe to the infusion bag. It is very important to take care of the pressure difference during drug transfer eject droplets, vapors and aerosols into the surroundings at work place, and is measured as one of the key routes of disclosure. 

The Closed System Drug-Transfer-Device introduced by Equashield is user-friendly and foolproof technology and an alternative with tight-seal double covering to stop vapors from evading and to keep the container sterile.  The closed –system is the totally amenable with rigid guidelines in the U.S and also in other countries.


The efficiency of Closed System Drug Transfer Device has been evaluated by EquaShiled is by decreasing the surface contamination using anti neoplastic agents during ambulant cancer chemotherapy invention center. 


The samples are collected from the entire cancer center. The sample that obtained for the first time was in June 2010 before cleaning the surrounding to evaluate baseline levels of infectivity of the present technique.  The 2nd samples were taken in August 2010 after the usage of the closed system transfer device and cleaning to measure if the infectivity was removed. The 3rd sample was taken in August 2011. Wipe samples were collected from 5 positions and 5 positions in the infusion area.  Some samples are collected from office areas. Samples were examined for 5-flurouracil and Cyclophosphamide.


The first sample set showed complete infectivity with Cyclophosphamide from all locations. The highest level of contamination was obtained on the door and the handle in the pharmacy department. Infectivity with 5-fluorouracil was found on the pharmacy dispensing counter in second collection sample.  The third samples showed no contamination with 5-fluorouracil or cyclophosphamide in the office, cancer center, and pharmacy or in infusion suite. 


Utilizing Closed System-Drug-Transfer Device can help your prevent risks from close contact with Hazardous Drugs. Especially medical staff found it useful as they have to deal with these perilous drugs every single day.